Enhancement of Antibody Immune Response to a Toxoplasma gondii SAG1-Encoded DNA Vaccine by Formulation with Aluminum Phosphate
نویسندگان
چکیده
منابع مشابه
Immune response to Toxoplasma gondii.
Oral-route infection with Toxoplasma gondii sporozoites or tachyzoites leads to the rapid spread of quick-replicating cytolytic tachyzoites throughout the whole body. Toxoplasma easily crosses the blood-retina, encephalic and placental barriers. The acute phase of this infection lasts for less than around ten days. The parasite causes a very strong type-1 response focused on the interferon-gamm...
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Immunization with plasmid DNA encoding various proteins promises to be a valuable vaccine approach especially if its immunogenicity could be optimized. In this study we show that the intramuscular delivery in dendritic cells (DC) of naked plasmid DNA encoding two proteins of herpes simplex virus (HSV) leads to the induction of significantly enhanced levels of resistance to viral challenge. Wher...
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ژورنال
عنوان ژورنال: Journal of Medical Sciences
سال: 2007
ISSN: 1682-4474
DOI: 10.3923/jms.2007.361.367